I. Achievement of Research Activities in 2016
Papers
M. Tanaka, M. Yoshimura, M. Ogawa, Y. Koyama, T. Shintani, K. Gomi
The C2H2-type transcription factor, FlbC, is involved in the transcriptional regulation of Aspergillus oryzae glucoamylase and protease genes specifically expressed in solid-state culture.
Appl. Microbiol. Biotechnol. ,100:5859–5868 (2016)
N. Li, E. Kunitake, M. Aoyama, M. Ogawa, K. Kanamaru, M. Kimura, Y. Koyama, T. Kobayashi
McmA-dependent and -independent regulatory systems governing expression of ClrB-regulated cellulase and hemicellulase genes in Aspergillus nidulans.
Molecular Microbiology, 102: 810–826 (2016)
Y. Shinohara, S. Takahashi, H. Osada, Y. Koyama
Identification of a novel sesquiterpene biosynthetic machinery involved in astellolide biosynthesis.
Scientific Reports, 15th Sep. 2016, doi: 10.1038/srep32865
A. Sato, K. Matsushima, K. Oshima, M. Hattori, Y. KoyamaM
Draft genome sequencing of the highly halotolerant and allopolyploid yeast Zygosaccharomyces rouxii NBRC 1876.
Genome Announc. February 2017 5:e01610-16; doi:10.1128/genomeA.01610-16
I. Nishimura, Y. Shiwa, A. Sato, T. Oguma, H. Yoshikawa, Y. Koyama
Comparative genomics of Tetragenococcus halophilus.
J. Gen. Appl. Microbiol., (In press)
II.Grant project
NISR has started a new project, which supports a research fund in the field of applied biology for the purpose of developing the fermentation and brewing industry.
1) 2016 NISR Research Grant
Masaki Mizunuma (Hiroshima University)
Analysis of the novel stress tolerance mechanism in yeast
Hikaru Seki (Osaka University)
Production of guaianolide sesquiterpene lactones in engineered yeast
Kentaro Takada (The University of Tokyo)
Functions of a novel signal molecule inducing sporulation in Streptomyces species
Kyoko Takahashi (Nihon University)
Regulation of allergic reactions of mast cells by intestinal bacteria and probiotics
Daisuke Umeno (Chiba University)
Evolutionary design of gene expression systems
2) 2016 NISR Young Investigator Research Grant
Takayoshi Awakawa (The University of Tokyo)
Construction of novel meroterpenoid biosynthetic pathway in Aspergillus oryzae
Makoto Hashimoto (Iwate Medical University)
Construction of biosynthetic machinery for polyketides with a bistetrahydrofuran moiety
Yujiro Higuchi(Kyushu University)
Functional analysis of SM proteins for heterologous protein production in Aspergillus oryzae
Takehito Nakazawa (Kyoto University)
Effects of secondary metabolism on sexual development and wood decay in Agaricomycetes
Ryo Nasuno (Nara Institute of Science and Technology)
A novel arginine metabolic pathway regulated by the yeast N-acetyltransferase Mpr1
Yuko Shimamura (University of Shizuoka)
Elucidation of the gene transfer mechanism of staphylococcal enterotoxin A
3) 2015 NISR Research Grant
Wataru Hashimoto（Kyoto University）
Structure-based conversion of the coenzyme specificity in polysaccharide-metabolizing reductases and their applications to biofuel production
Makoto Kimura（Nagoya University）
A basic study toward metabolic engineering of sesquiterpenes
Akira Nakagawa（Ishikawa Prefectural University）
Fermentative production of tetrahydropapaverine and its derivatives using Escherichia coli
Masataka Tsuda（Tohoku University）
Comprehensive analysis of iron-regulated genome expression in environmental bacterium
Takeshi Watanabe（Niigata University）
Mechanism of enzymatic degradation of recalcitrant structural polysaccharide with crystalline structure
4) 2015 NISR Young Investigator Research Grant
Ken-ichi Hashimoto（Tokyo Denki University）
Development of a novel fermentation technology using mechanosensitive channels
Daisuke Hira（Sojo University）
Structure of hydrazine synthase, an electron transfer complex
Hiroto Hirayama（RIKEN）
Functional analysis of a novel endo-O-mannosidase in budding yeast, Saccharomyces cerevisiae
Tomokazu Ito （Nagoya University）
Fermentative production of ophthalmic acid
Chiho Suzuki-Minakuchi（The University of Tokyo）
Degradation pathways of anaerobic benzene-degrading bacteria
5) 2014 NISR Research Grant
Akinori Kato（Kinki University）
Control of bacterial lipopolysaccharide modifications and rare metal nanoparticle production