年報2009

I. Outline of the Noda Institute for Scientific Research

C. S. Escaño, P. R. Juvvadi, F. J. Jin, T. Takahashi, Y. Koyama, S. Yamashita, J. Maruyama, K. Kitamoto: Disruption of the Aopex11-1 gene involved in peroxisome proliferation leads to impaired Woronin body formation in Aspergillus oryzae.
　Reproduced from Eukaryot. Cell, 8: 296-305 (2009) by copyright permission of American Society for Microbiology
Y. Seshime, P. R. Juvvadi, M. Tokuoka, Y. Koyama, K. Kitamoto, Y. Ebizuka, I. Fujii: Functional expression of the Aspergillus flavus PKS-NRPS hybrid CpaA involved in the biosynthesis of cyclopiazonic acid.
　Reproduced from Bioorg. Med. Chem. Lett., 19: 3288-3292 (2009) by copyright permission of Elsevier Ltd.
T. Takahashi, F. J. Jin, Y. Koyama: Nonhomologous end-joining deficiency allows large chromosomal deletions to be produced by replacement-type recombination in Aspergillus oryzae.
　Reproduced from Fungal Genet. Biol., 46: 815-824 (2009) by copyright permission of Elsevier Inc.

Taketomo FUJIWARA (Shizuoka University): Development of halophilic protein expression system capable of creating a productive enzyme
Masato IKEDA (Shinshu University): Elucidation of genes relevant to microaerobic growth of Corynebacterium glutamicum
Takashi KAWAGUCHI (Osaka Prefecture University): Establishment of marker-recycling method in filamentous fungi and development of an Aspergillus aculeatus multi-auxotrophic host
Fujio KAWAMURA (Rikkyo University): Development of a translation system highly expressing the target gene in B. subtilis
Hiroshi KITAGAKI (Saga University): A research on mitochondria-targeted breeding of a novel brewery yeast

Jiro ARIMA (Tottori University): Molecular evolution of Streptomyces serine peptidase for the synthesis of β-alanyl-histidine
Hiroki HIGASHIBATA (Toyo University): Analysis of tRNA modification system in halophilic archaea
Takashi HIRASAWA (Osaka University): Fundamental researches on increasing applicability of Saccharomyces cerevisiae as the host cells for production of useful metabolites
Hisashi MURAMATSU (Kochi University): Molecular breeding of enzymes catalyzing asymmetric reactions: Aimed to provide a non-natural amino acid chemical library
Akihiro SAITO (Chiba University): Exploration of novel transporter proteins for oligosaccharides using the ATPase (MsiK)
Kaneyoshi YAMAMOTO (Hosei University): Regulation of genes expression on Escherichia coli genome with communications among microbes

Yasuo OHNISHI (The University of Tokyo): Studies on regulation of secondary metabolism and morphogenesis of Streptomyces by DNA microarray analysis